In episode 27 of We’re doomed, We’re saved , the bio revolution podcast Andreas Horchler and Louise von Stechow talk about the potential of Artificial Intelligence (AI) in drug discovery and development. The pharma industry is struggling with high development costs and failure rates. Can AI help to overcome those challenges, and what is hype and what is reality?
Epsiode 26: The future of medicine - trends, technologies and skills
In episode 26 of We’re doomed we’re saved we talk about the future trends in medicine, such as technologization, virtualization, predictive orientation and patient centration. These trends are corroborated by new technologies, such as artificial intelligence (AI), telemedicine, wearable devices and smart sensors.
Listen to We're doomed, We're saved, the bio revolution podcast with Andreas Horchler and Louise von Stechow here.
Epsiode 25: 1.5 years of LLMs - hope, hype and hallucination
Epsiode 24: Artificial intelligence - hope for rare desease patients?
Rare or orphan diseases affect only a small percentage of the population and often lack effective treatments. While rare individually, in total, more than 350 million people worldwide live with rare diseases. Many of these are very hard to diagnose, let alone cure, and the rarity of patients challenges the development of novel treatments.
To make the development of drugs for rare diseases more efficient and successful, artificial intelligence (AI) could be an important ally not only for drug makers but also for patients.
Epsiode 23: New biotechnologies: revolution or evolution?
A revolution driven by novel biotechnologies (gene editing, neuroprosthetics, synthetic biology, and artificial intelligence in biotech) has the potential to not only change the way we live but the very foundations of our lives – our biology.
But is the so-called biorevolution a real "scientific revolution"?
In the new episode of "We're Doomed, We're Saved," Andreas Horchler and Louise von Stechow look at the biorevolution from different angles, examining its transformative potential and comparing it to revolutions that came before.
Epsiode 22: Polygenic risk scores – The Truth in our Genes
Polygenic risk scores (PRS), put simply, look at gene variants across the human genome in order to determine an individual's risk of getting a disease, from different types of cancer to type II diabetes. PRS could complement current risk prediction models and lead to a more accurate risk prediction.
Epsiode 21: Cell rejuvenation – Resetting the biological clock
Aging is a dynamic process characterized by the accumulation of cell damage, tissue, and organ degeneration, and diminished function. This process of decline appears to be an inevitable aspect of human existence. In recent years, however, advancements in scientific understanding of aging bring us closer to extending the human lifespan.
With their guests, Dr. Jürgen Reess and Prof. Hartmut Geiger, founders of Moglingbio, Louise von Stechow and Andreas Horchler explore the complex science underlying the process of aging and the challenges faced by the budding longevity industry. They talk about the potential for rejuvenating aged cells in human tissues and the ethical considerations of extending the human lifespan.
Content and Editing: Louise von Stechow und Andreas Horchler
Disclaimer: Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Image: Marcelo Lea via Unsplash
Epsiode 20: Women’s Health - Humanity’s other half
Women make up about half of humanity. Yet, the medical community and the pharmaceutical and biotech industries have long adopted an androcentric view of disease biology and healthcare needs, perceiving women as a specialized or atypical demographic.
In episode 20 of We're Doomed, We're Saved, we talk to two biotech experts, Catenion's Dr. Ana Rita Da Costa and Dr. Pascal Joly, to discuss how the biotech industry and healthcare community slowly, but steadily, change and adapt to the needs of half of their customers: women.
Content and Editing: Louise von Stechow und Andreas Horchler
Disclaimer: Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Image: Danilo Alvesd via Unsplash
Epsiode 19: mRNA Therapeutics - New applications for an old molecule
RNA, one of the oldest and most versatile biomolecules, has recently entered the therapeutic arena. While for many observers the success of mRNA vaccines seemed to come out of the blue, its build on the fundament of research that has large gone ignored.
Now mRNA therapeutics are enjoying the limelight of great economic success for companies like BioNTech / Pfizer and Moderna, and the awarding of the 2023 Nobel Prize to two mRNA researchers. But with the fame also comes a huge public backlash of anti-vaxxers who fear the perceived novelty of mRNAs.
In the 19th episode of We're doomed, we're saved Louise von Stechow and Andreas Horchler talk with their guest, mRNA researcher Lucia Lapazio who has known the field before and after the hype.
Content and Editing: Louise von Stechow und Andreas Horchler
Disclaimer: Louise von Stechow, Andreas Horchler and their guests express their personal opinions, which are founded on research on the respective topics, but do not claim to give medical, investment or even life advice in the podcast.
Image: s-ASFul4w-o58- via Unsplash